node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HNE_3544 | HNE_3545 | HNE_3544 | HNE_3545 | Conserved hypothetical protein; Identified by similarity to GB:CAD85056.1; match to protein family HMM PF06155. | Conserved hypothetical protein; Identified by similarity to GB:AAK22095.1; match to protein family HMM PF03966; Belongs to the UPF0434 family. | 0.855 |
HNE_3544 | HNE_3546 | HNE_3544 | HNE_3546 | Conserved hypothetical protein; Identified by similarity to GB:CAD85056.1; match to protein family HMM PF06155. | ATP-dependent protease, La family; Identified by match to protein family HMM PF02190. | 0.768 |
HNE_3544 | HNE_3547 | HNE_3544 | HNE_3547 | Conserved hypothetical protein; Identified by similarity to GB:CAD85056.1; match to protein family HMM PF06155. | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.723 |
HNE_3545 | HNE_3544 | HNE_3545 | HNE_3544 | Conserved hypothetical protein; Identified by similarity to GB:AAK22095.1; match to protein family HMM PF03966; Belongs to the UPF0434 family. | Conserved hypothetical protein; Identified by similarity to GB:CAD85056.1; match to protein family HMM PF06155. | 0.855 |
HNE_3545 | HNE_3546 | HNE_3545 | HNE_3546 | Conserved hypothetical protein; Identified by similarity to GB:AAK22095.1; match to protein family HMM PF03966; Belongs to the UPF0434 family. | ATP-dependent protease, La family; Identified by match to protein family HMM PF02190. | 0.834 |
HNE_3545 | HNE_3547 | HNE_3545 | HNE_3547 | Conserved hypothetical protein; Identified by similarity to GB:AAK22095.1; match to protein family HMM PF03966; Belongs to the UPF0434 family. | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.711 |
HNE_3546 | HNE_3544 | HNE_3546 | HNE_3544 | ATP-dependent protease, La family; Identified by match to protein family HMM PF02190. | Conserved hypothetical protein; Identified by similarity to GB:CAD85056.1; match to protein family HMM PF06155. | 0.768 |
HNE_3546 | HNE_3545 | HNE_3546 | HNE_3545 | ATP-dependent protease, La family; Identified by match to protein family HMM PF02190. | Conserved hypothetical protein; Identified by similarity to GB:AAK22095.1; match to protein family HMM PF03966; Belongs to the UPF0434 family. | 0.834 |
HNE_3546 | HNE_3547 | HNE_3546 | HNE_3547 | ATP-dependent protease, La family; Identified by match to protein family HMM PF02190. | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.798 |
HNE_3547 | HNE_3544 | HNE_3547 | HNE_3544 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Conserved hypothetical protein; Identified by similarity to GB:CAD85056.1; match to protein family HMM PF06155. | 0.723 |
HNE_3547 | HNE_3545 | HNE_3547 | HNE_3545 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Conserved hypothetical protein; Identified by similarity to GB:AAK22095.1; match to protein family HMM PF03966; Belongs to the UPF0434 family. | 0.711 |
HNE_3547 | HNE_3546 | HNE_3547 | HNE_3546 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | ATP-dependent protease, La family; Identified by match to protein family HMM PF02190. | 0.798 |
HNE_3547 | dnaJ | HNE_3547 | HNE_0761 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.753 |
HNE_3547 | gor | HNE_3547 | HNE_0707 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Glutathione-disulfide reductase; Maintains high levels of reduced glutathione. | 0.931 |
HNE_3547 | groL | HNE_3547 | HNE_1962 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.656 |
HNE_3547 | grpE | HNE_3547 | HNE_3318 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.861 |
HNE_3547 | hslU | HNE_3547 | HNE_2034 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.856 |
HNE_3547 | hslV | HNE_3547 | HNE_2033 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | ATP-dependent protease HslVU; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.849 |
HNE_3547 | trxB | HNE_3547 | HNE_0548 | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Thioredoxin-disulfide reductase; Identified by similarity to SP:P09625; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. | 0.743 |
dnaJ | HNE_3547 | HNE_0761 | HNE_3547 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.753 |