STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBPutative homoserine kinase protein; Belongs to the pseudomonas-type ThrB family. (316 aa)    
Predicted Functional Partners:
NE2369
Homoserine dehydrogenase:ACT domain.
 
 
 0.922
thrC
thrC; probable threonine synthase protein.
  
 
 0.916
PatB
Aminotransferases class-I.
   
 
  0.810
metH
metH Methionine synthase I, cobalamin-binding domain; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.809
ilvE
Aminotransferases class-IV; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.805
metY
Cys/Met metabolism pyridoxal-phosphate-dependent enzymes.
    
  0.804
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.801
NE0380
Iron-sulfur-dependent L-serine dehydratase single chain form.
   
 
  0.800
NE0575
Bacterial transferase hexapeptide repeat.
   
 
  0.800
metZ
Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
  0.800
Your Current Organism:
Nitrosomonas europaea
NCBI taxonomy Id: 228410
Other names: N. europaea ATCC 19718, Nitrosomonas europaea ATCC 19718, Nitrosomonas europaea str. ATCC 19718
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