STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mucD-2mucD; serine protease MucD precursor; Belongs to the peptidase S1C family. (496 aa)    
Predicted Functional Partners:
NE2330
Hypothetical protein; InterPro IPR001687 COGs COG3073.
  
 
 0.904
NE2328
Putative thioredoxin.
  
   0.838
rpoE1
Sigma factor, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.686
rkpA
Similar to (AF285636) putative type I polyketide synthase WcbR [Burkholderia mallei], evalue=0.00e+00, 41% identity.
  
 0.626
NE1444
TPR repeat.
  
 0.606
lepA
GTP-binding elongation factor:Elongation factor Tu domain 2; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
     
 0.527
NE0049
Sensory transduction histidine kinases.
  
  
 0.516
NE2332
CBS domain.
 
   
 0.456
rsfS
Domain of unknown function DUF143:Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
   0.428
NE1711
Membrane-associated Zn-dependent proteases 1.
 
  
 0.412
Your Current Organism:
Nitrosomonas europaea
NCBI taxonomy Id: 228410
Other names: N. europaea ATCC 19718, Nitrosomonas europaea ATCC 19718, Nitrosomonas europaea str. ATCC 19718
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