STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEQ015NEQ015; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (352 aa)    
Predicted Functional Partners:
NEQ014
NEQ014; C4-dicarboxylate transporter [Magnetococcus sp]; COG1275: Tellurite resistance protein and related permeases.
       0.561
dcd
NEQ316; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
     
 0.468
NEQ329
NEQ329; dCTP deaminase [Methanosarcina acetivorans]; COG0717: Deoxycytidine deaminase; IPR003232: dCTP Deaminase.
     
 0.468
NEQ238
NEQ238; Conserved hypothetical protein [Methanococcus jannaschii]; COG2890: Predicted rRNA or tRNA methylase; IPR000051: SAM (and some other nucleotide) binding motif; IPR002052: N-6 Adenine-specific DNA methylase; IPR002296: N6 adenine-specific DNA methyltransferase, N12 class.
  
   0.450
rnj
NEQ466; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
   
   0.446
rnhB
NEQ063; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
     
 0.401
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.