STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEQ248NEQ248; 3' exoribonuclease [Pyrococcus furiosus]; COG0689: RNase PH; IPR001247: 3' exoribonuclease family. (233 aa)    
Predicted Functional Partners:
NEQ111
NEQ111; 3' exoribonuclease [Archaeglobus fulgidus]; COG2123: RNase PH-related exoribonuclease; IPR001247: 3' exoribonuclease family.
  
 0.999
NEQ184
NEQ184; Conserved hypothetical protein [Archaeoglobus fulgidus]; COG1097: RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain); IPR000958: KH domain.
 
 0.999
rps4
NEQ247; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
  0.961
NEQ031
NEQ031; Predicted RNA binding protein; COG1094: Predicted RNA-binding protein (contains KH domains); IPR001472: Bipartite nuclear localization signal.
   
  0.935
dnaG
NEQ341; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
   
 0.925
NEQ342
NEQ342; Nucleolar protein [Sulfolobus tokodaii]; COG1498: Protein implicated in ribosomal biogenesis, Nop56p homolog; IPR002687: Putative snoRNA binding domain.
   
 0.912
flpA
NEQ125; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
   
 0.910
rpl7ae
NEQ319; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
   
 0.894
rps11
NEQ069; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
   
 0.882
rps6e
NEQ105; Ribosomal protein S6E [Methanopyrus kandeleri]; COG2125: Ribosomal protein S6E (S10); IPR001377: Ribosomal protein S6e; IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eS6 family.
    
  0.871
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.