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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEQ345aNEQ345a; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family. (299 aa)    
Predicted Functional Partners:
rpl18a
NEQ346; LSU ribosomal protein LX [Pyrococcus horikowshii]; COG2157: Ribosomal protein L20A (L18A); IPR002768: Ribosomal LX protein.
       0.773
NEQ347
NEQ347; Conserved hypothetical protein [Methanosarcina acetivorans]; COG1355: Predicted dioxygenase; IPR002737: Protein of unknown function DUF52; Belongs to the MEMO1 family.
       0.682
NEQ348
NEQ348; Putative histone A2 [Methanococcus jannaschii]; COG2036: Histones H3 and H4; IPR000947: Histone-like transcription factor (CBF/NF-Y) and archaeal histone, subunit A; IPR000166: Histone-fold/TFIID-TAF/NF-Y domain.
       0.627
NEQ349
NEQ349; ATP-dependent protease La [Archaeoglobus fulgidus]; COG1067: Predicted ATP-dependent protease; IPR001984: ATP-dependent serine proteases, Lon family; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR003593: AAA ATPase superfamily.
       0.568
NEQ350
NEQ350; Conserved hypothetical protein [Thermoplasma volcanium]; COG2151: Putative aromatic ring hydroxylating enzyme; IPR002744: Domain of unknown function DUF59.
       0.517
NEQ345
NEQ345; Ribonucleoside triphosphate reductase; COG1328: Oxygen-sensitive ribonucleoside-triphosphate reductase.
       0.475
NEQ343
NEQ343; Hypothetical protein [Pyrococcus abyssi]; COG0693: Putative intracellular protease/amidase.
       0.426
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
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