STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEQ409NEQ409; Helicase-related protein [Pyrococcus furiosus]; COG1201: Lhr-like helicases; IPR001472: Bipartite nuclear localization signal. (260 aa)    
Predicted Functional Partners:
NEQ003
NEQ003; Large helicase-related protein [Pyrococcus abyssi]. SPLIT See NEQ409; COG1201: Lhr-like helicases; IPR001410: DEAD/DEAH box helicase; IPR001472: Bipartite nuclear localization signal; IPR001650: Helicase C-terminal domain; IPR003593: AAA ATPase superfamily.
 
      0.900
NEQ410
NEQ410; ATPase subunit I [Clostridium thermocellum]; COG1269: Archaeal/vacuolar-type H+-ATPase subunit I; IPR002490: V-type ATPase 116kDa subunit family.
       0.773
NEQ407
NEQ407.
       0.541
radA
NEQ426; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
  
 
 0.527
NEQ057
NEQ057; Involved in regulation of DNA replication.
   
   0.487
NEQ270
NEQ270; Elongation factor Tu [Pyrococcus abyssi]; COG0050: GTPases - translation elongation factors; IPR000795: GTP-binding elongation factor; IPR001687: ATP/GTP-binding site motif A (P-loop).
   
 
 0.464
rnz
NEQ064; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
   
   0.449
rad50
NEQ256; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
   
   0.446
NEQ369
NEQ369; DEAD box helicase [Sulfolobus solfataricus]; COG1061: DNA or RNA helicases of superfamily II; IPR001410: DEAD/DEAH box helicase; IPR001650: Helicase C-terminal domain.
   
   0.446
top6B
NEQ144; Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
   
   0.443
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
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