STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEQ438NEQ438; Conserved hypothetical protein [Pyrococcus abyssi]; COG1293: Predicted RNA-binding protein homologous to eukaryotic snRNP. (332 aa)    
Predicted Functional Partners:
NEQ506
NEQ506; Conserved hypothetical protein [Sulfolobus solfataricus]; COG1293: Predicted RNA-binding protein homologous to eukaryotic snRNP.
 
     0.915
NEQ440
NEQ440; Methyltransferase related protein [Methanothermobacter thermautotrophicus]; COG1041: Predicted DNA modification methylase; IPR000051: SAM (and some other nucleotide) binding motif; IPR002052: N-6 Adenine-specific DNA methylase; IPR001472: Bipartite nuclear localization signal.
       0.788
NEQ435
NEQ435; Hypothetical protein [Archaeoglobus fulgidus]; COG2433: Uncharacterized ACR.
 
     0.764
NEQ442
NEQ442; Hypothetical protein; IPR001969: Eukaryotic and viral aspartic protease active site.
       0.705
rpl21e
NEQ397; LSU ribosomal protein L21E [Pyrococcus furiosus]; COG2139: Ribosomal protein L21E; IPR001147: Ribosomal protein L21E; IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eL21 family.
  
 
   0.697
rpl13
NEQ207; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.652
rpl14
NEQ092; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.639
rpl5
NEQ093; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
   
   0.636
rpl24
NEQ257; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
   0.634
rpl2
NEQ361; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
   0.628
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.