STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEQ521NEQ521; Protease subunit of the proteasome [Methanopyrus kandleri]; COG0638: Proteasome protease subunit; IPR001353: Multispecific proteases of the proteasome. (250 aa)    
Predicted Functional Partners:
psmB
NEQ203; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
 0.999
NEQ186
NEQ186; 26S proteasome subunit P45 family [Sulfolobus tokodaii]; COG1222: ATP-dependent 26S proteasome regulatory subunit; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001939: AAA-protein (ATPases associated with various cellular activities); IPR003593: AAA ATPase superfamily.
 
 0.982
NEQ475
NEQ475; Cell division control protein 48 [Pyrococcus furiosus]; COG0464: ATPases of the AAA+ class; IPR003338: Amino-terminal subdomain, VAT-Nn; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001939: AAA-protein (ATPases associated with various cellular activities); IPR001472: Bipartite nuclear localization signal; IPR003593: AAA ATPase superfamily.
 
 0.860
fusA
NEQ543; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
  
 
 0.632
rpl15e
NEQ181; LSU ribosomal protein L15E; [Pyrococcus furiosus]; COG1632: Ribosomal protein L15E; IPR000439: Ribosomal protein L15e; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eL15 family.
   
 0.616
ef1b
NEQ220; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
   
  
 0.597
NEQ141
NEQ141; GroEL chaperonin [Methanopyrus kandeleri]; COG0459: Chaperonin GroEL (HSP60 family); IPR002194: Chaperonins TCP-1; IPR002423: TCP-1 (Tailless complex polypeptide)/cpn60 chaperonin family; IPR001844: Chaperonin cpn60 (60Kd subunit); Belongs to the TCP-1 chaperonin family.
 
 
 0.577
NEQ523
NEQ523; Conserved hypothetical protein [Pyrococcus abyssi]; COG0037: Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; IPR000541: Uncharacterized protein family UPF0021.
       0.571
aspS
NEQ535; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp).
   
  
 0.561
leuS
NEQ239; Isoleucine tRNA synthetase [Methanococcus jannaschii]; COG0495: Leucyl-tRNA synthetase; COG0143: Methionyl-tRNA synthetase; IPR002300: t-RNA synthetase, class Ia; IPR002308: Cysteinyl-tRNA synthetase; IPR001412: Aminoacyl-transfer RNA synthetases class-I; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
   0.549
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.