node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHF93280.1 | SHF93319.1 | SAMN05444372_101225 | SAMN05444372_101227 | Ribonucleoside-diphosphate reductase beta chain. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
SHF93280.1 | SHF96683.1 | SAMN05444372_101225 | SAMN05444372_101367 | Ribonucleoside-diphosphate reductase beta chain. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.864 |
SHF93280.1 | SHG45773.1 | SAMN05444372_101225 | SAMN05444372_10663 | Ribonucleoside-diphosphate reductase beta chain. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.749 |
SHF93280.1 | SHH12240.1 | SAMN05444372_101225 | SAMN05444372_11618 | Ribonucleoside-diphosphate reductase beta chain. | Amino acid adenylation domain-containing protein. | 0.720 |
SHF93280.1 | SHH12269.1 | SAMN05444372_101225 | SAMN05444372_11619 | Ribonucleoside-diphosphate reductase beta chain. | Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.720 |
SHF93280.1 | adk | SAMN05444372_101225 | SAMN05444372_10664 | Ribonucleoside-diphosphate reductase beta chain. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.916 |
SHF93280.1 | cmk | SAMN05444372_101225 | SAMN05444372_10517 | Ribonucleoside-diphosphate reductase beta chain. | Cytidylate kinase. | 0.892 |
SHF93280.1 | gmk | SAMN05444372_101225 | SAMN05444372_101411 | Ribonucleoside-diphosphate reductase beta chain. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.882 |
SHF93280.1 | ndk | SAMN05444372_101225 | SAMN05444372_11334 | Ribonucleoside-diphosphate reductase beta chain. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.891 |
SHF93280.1 | pyrH | SAMN05444372_101225 | SAMN05444372_11150 | Ribonucleoside-diphosphate reductase beta chain. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.890 |
SHF93319.1 | SHF93280.1 | SAMN05444372_101227 | SAMN05444372_101225 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase beta chain. | 0.999 |
SHF93319.1 | SHF96683.1 | SAMN05444372_101227 | SAMN05444372_101367 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.864 |
SHF93319.1 | SHG45773.1 | SAMN05444372_101227 | SAMN05444372_10663 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.785 |
SHF93319.1 | adk | SAMN05444372_101227 | SAMN05444372_10664 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.920 |
SHF93319.1 | cmk | SAMN05444372_101227 | SAMN05444372_10517 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Cytidylate kinase. | 0.902 |
SHF93319.1 | gmk | SAMN05444372_101227 | SAMN05444372_101411 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.895 |
SHF93319.1 | ndk | SAMN05444372_101227 | SAMN05444372_11334 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.901 |
SHF93319.1 | pyrH | SAMN05444372_101227 | SAMN05444372_11150 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.897 |
SHF96683.1 | SHF93280.1 | SAMN05444372_101367 | SAMN05444372_101225 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Ribonucleoside-diphosphate reductase beta chain. | 0.864 |
SHF96683.1 | SHF93319.1 | SAMN05444372_101367 | SAMN05444372_101227 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.864 |