STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (566 aa)    
Predicted Functional Partners:
SHH15476.1
Isochorismate synthase.
 
 
 0.983
SHG21607.1
O-succinylbenzoate synthase.
 
  
 0.949
SHG29749.1
O-succinylbenzoic acid--CoA ligase.
 
 
 0.914
menB
1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
 
 0.895
SHG95434.1
Pimeloyl-ACP methyl ester carboxylesterase.
   
 
 0.870
menA
1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.845
SHF95423.1
Pimeloyl-ACP methyl ester carboxylesterase.
   
 
 0.802
SHH15446.1
Uncharacterized domain 1-containing protein.
 
   
 0.694
SHH09947.1
L-alanine-DL-glutamate epimerase.
 
  
 0.619
SHF89268.1
Pimeloyl-ACP methyl ester carboxylesterase.
  
 
 0.596
Your Current Organism:
Flavobacterium micromati
NCBI taxonomy Id: 229205
Other names: CIP 108161, DSM 17659, F. micromati, Flavobacterium micromati Van Trappen et al. 2004, LMG 21919, LMG:21919
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