STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1C3YIX0Tim44 domain-containing protein. (554 aa)    
Predicted Functional Partners:
FG05578.1
Uncharacterized protein.
   
 0.987
PAM16
Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family.
   
 0.972
FG00305.1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
   
 0.965
PAM18
Mitochondrial import inner membrane translocase subunit TIM14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity); Belongs to the TIM14 family.
    
 0.943
FG06415.1
Uncharacterized protein.
   
 0.930
FG06154.1
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.921
A0A1C3YK26
Uncharacterized protein.
   
 0.879
TIM50
Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity).
   
 0.852
TIM21
Mitochondrial import inner membrane translocase subunit TIM21; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity).
    
 0.769
FG07331.1
Uncharacterized protein.
   
 
 0.761
Your Current Organism:
Fusarium graminearum
NCBI taxonomy Id: 229533
Other names: F. graminearum PH-1, Fusarium graminearum PH-1, Gibberella zeae PH-1
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