node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A1C3YHX4 | A0A1C3YIL3 | A0A1C3YHX4 | A0A1C3YIL3 | Uncharacterized protein. | Chromatin modification-related protein. | 0.956 |
A0A1C3YHX4 | A0A1C3YK01 | A0A1C3YHX4 | A0A1C3YK01 | Uncharacterized protein. | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.981 |
A0A1C3YHX4 | ARP4 | A0A1C3YHX4 | Q4IPI4 | Uncharacterized protein. | Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes [...] | 0.939 |
A0A1C3YHX4 | EPL1 | A0A1C3YHX4 | Q4I5V3 | Uncharacterized protein. | Enhancer of polycomb-like protein 1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity). | 0.992 |
A0A1C3YHX4 | ESA1 | A0A1C3YHX4 | Q4IEV4 | Uncharacterized protein. | Histone acetyltransferase ESA1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recru [...] | 0.951 |
A0A1C3YHX4 | FG06040.1 | A0A1C3YHX4 | I1SB04 | Uncharacterized protein. | MRG domain-containing protein. | 0.951 |
A0A1C3YHX4 | FG07335.1 | A0A1C3YHX4 | I1RT41 | Uncharacterized protein. | Uncharacterized protein. | 0.858 |
A0A1C3YHX4 | RVB1 | A0A1C3YHX4 | Q4ICA8 | Uncharacterized protein. | RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. | 0.767 |
A0A1C3YHX4 | SWC4 | A0A1C3YHX4 | Q4HY90 | Uncharacterized protein. | SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). | 0.986 |
A0A1C3YHX4 | YAF9 | A0A1C3YHX4 | Q4I7S1 | Uncharacterized protein. | Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). | 0.973 |
A0A1C3YIL3 | A0A1C3YHX4 | A0A1C3YIL3 | A0A1C3YHX4 | Chromatin modification-related protein. | Uncharacterized protein. | 0.956 |
A0A1C3YIL3 | A0A1C3YK01 | A0A1C3YIL3 | A0A1C3YK01 | Chromatin modification-related protein. | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.911 |
A0A1C3YIL3 | ARP4 | A0A1C3YIL3 | Q4IPI4 | Chromatin modification-related protein. | Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes [...] | 0.895 |
A0A1C3YIL3 | EPL1 | A0A1C3YIL3 | Q4I5V3 | Chromatin modification-related protein. | Enhancer of polycomb-like protein 1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity). | 0.979 |
A0A1C3YIL3 | ESA1 | A0A1C3YIL3 | Q4IEV4 | Chromatin modification-related protein. | Histone acetyltransferase ESA1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recru [...] | 0.960 |
A0A1C3YIL3 | FG06040.1 | A0A1C3YIL3 | I1SB04 | Chromatin modification-related protein. | MRG domain-containing protein. | 0.851 |
A0A1C3YIL3 | FG07335.1 | A0A1C3YIL3 | I1RT41 | Chromatin modification-related protein. | Uncharacterized protein. | 0.602 |
A0A1C3YIL3 | RVB1 | A0A1C3YIL3 | Q4ICA8 | Chromatin modification-related protein. | RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. | 0.540 |
A0A1C3YIL3 | SWC4 | A0A1C3YIL3 | Q4HY90 | Chromatin modification-related protein. | SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). | 0.906 |
A0A1C3YIL3 | YAF9 | A0A1C3YIL3 | Q4I7S1 | Chromatin modification-related protein. | Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). | 0.850 |