Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACN38_g794Protein-serine/threonine kinase. (441 aa)    
Predicted Functional Partners:
ACN38_g9403
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.915
ACN38_g10789
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.896
ACN38_g2715
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.829
ACN38_g9674
Peripheral subunit-binding (PSBD) domain-containing protein.
    
 0.725
ACN38_g3091
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.725
ACN38_g12714
Uncharacterized protein.
    
 0.722
ACN38_g3302
Dihydrolipoyl dehydrogenase.
    
 0.722
ACN38_g12533
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.709
ACN38_g9669
ATP-dependent Clp protease proteolytic subunit.
   
 0.662
hsp60
Heat shock protein 60; Belongs to the chaperonin (HSP60) family.
    
  0.642
Your Current Organism:
Penicillium nordicum
NCBI taxonomy Id: 229535
Other names: P. nordicum
Server load: medium (50%) [HD]