Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
ACN38_g4711DBF4-type domain-containing protein. (642 aa)    
Predicted Functional Partners:
ACN38_g5311
Protein kinase domain-containing protein.
   
 0.998
ACN38_g7586
DNA helicase; Belongs to the MCM family.
   
 0.997
ACN38_g1853
DNA helicase; Belongs to the MCM family.
    
 0.997
ACN38_g5528
DNA helicase; Belongs to the MCM family.
   
 0.996
ACN38_g5686
DNA helicase; Belongs to the MCM family.
   
 0.993
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.991
ACN38_g11469
DNA helicase; Belongs to the MCM family.
   
 0.991
ACN38_g2893
SLD3 domain-containing protein.
    
 0.980
ACN38_g11340
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.978
ACN38_g4761
Zf-primase domain-containing protein.
    
 0.977
Your Current Organism:
Penicillium nordicum
NCBI taxonomy Id: 229535
Other names: P. nordicum
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