Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACN38_g3371E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2140 aa)    
Predicted Functional Partners:
ACN38_g2728
HECT domain-containing protein.
   
 0.997
mus8
Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.974
ACN38_g6865
RING-CH-type domain-containing protein.
   
 
 0.957
ACN38_g4796
Homeobox domain-containing protein.
    
 
 0.937
ACN38_g7342
Uncharacterized protein.
    
 
 0.915
ACN38_g1858
Uncharacterized protein.
    
 
 0.887
ACN38_g3075
RING-CH-type domain-containing protein.
   
 
 0.843
ACN38_g8649
Uncharacterized protein.
    
   0.820
ACN38_g9483
Uncharacterized protein.
    
   0.819
ACN38_g2866
UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.
    
 0.799
Your Current Organism:
Penicillium nordicum
NCBI taxonomy Id: 229535
Other names: P. nordicum
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