Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACN38_g3663Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)    
Predicted Functional Partners:
ACN38_g930
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
   
 0.999
ACN38_g6276
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.997
ACN38_g5992
Uncharacterized protein.
  
 0.992
ACN38_g2802
Transket_pyr domain-containing protein.
   
 0.992
ACN38_g7741
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.969
ACN38_g11620
Citrate synthase; Belongs to the citrate synthase family.
  
 0.968
ACN38_g371
Citrate synthase; Belongs to the citrate synthase family.
  
 0.968
ACN38_g1386
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 0.958
ACN38_g1065
ATP-grasp domain-containing protein.
   
 0.957
ACN38_g1901
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.957
Your Current Organism:
Penicillium nordicum
NCBI taxonomy Id: 229535
Other names: P. nordicum
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