Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACN38_g3421Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (763 aa)    
Predicted Functional Partners:
ACN38_g247
DNA_mis_repair domain-containing protein.
    
 0.991
ACN38_g9551
Uncharacterized protein.
    
 0.990
ACN38_g10866
DNA_mis_repair domain-containing protein.
    
 0.972
ACN38_g11125
Uncharacterized protein.
    
 0.890
ACN38_g9322
ERCC4 domain-containing protein.
    
 0.863
ACN38_g564
Uncharacterized protein.
     
 0.825
ACN38_g11978
MutL_C domain-containing protein.
   
 0.807
SLX1
Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
   
 
 0.807
ACN38_g1026
Uncharacterized protein.
     
 0.781
ACN38_g2855
DNA_LIGASE_A3 domain-containing protein.
   
 0.768
Your Current Organism:
Penicillium nordicum
NCBI taxonomy Id: 229535
Other names: P. nordicum
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