STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEQ80_03565Unannotated protein. (329 aa)    
Predicted Functional Partners:
DEQ80_03570
Unannotated protein.
       0.752
gyrB
Unannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.604
GCA_001050195_02187
Unannotated protein.
       0.604
GCA_001050195_02191
Unannotated protein.
       0.555
DEQ80_03575
Unannotated protein.
       0.517
GCA_001050195_02185
Unannotated protein.
       0.417
Your Current Organism:
Anaerolinea thermolimosa
NCBI taxonomy Id: 229919
Other names: A. thermolimosa, Anaerolinea thermolimosa Yamada et al. 2006, DSM 16554, JCM 12577, anaerobic filamentous bacterium IMO-1, strain IMO-1
Server load: low (16%) [HD]