STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL72483.1Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (678 aa)    
Predicted Functional Partners:
KPL72481.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
KPL72971.1
Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
KPL70388.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.979
KPL72482.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.840
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.770
KPL70454.1
Crystallin; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.622
KPL70387.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.594
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.527
KPL70312.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.489
KPL72484.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.481
Your Current Organism:
Leptolinea tardivitalis
NCBI taxonomy Id: 229920
Other names: DSM 16556, JCM 12579, L. tardivitalis, Leptolinea tardivitalis Yamada et al. 2006, anaerobic filamentous bacterium YMTK-2, strain YMTK-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.