STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL71813.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)    
Predicted Functional Partners:
KPL71812.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.791
KPL71919.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.581
KPL71814.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.549
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.496
KPL72410.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.486
KPL74016.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.470
glyS
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.468
KPL70309.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.443
KPL71122.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 0.421
KPL71594.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.408
Your Current Organism:
Leptolinea tardivitalis
NCBI taxonomy Id: 229920
Other names: DSM 16556, JCM 12579, L. tardivitalis, Leptolinea tardivitalis Yamada et al. 2006, anaerobic filamentous bacterium YMTK-2, strain YMTK-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.