Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdxBErythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (376 aa)    
Predicted Functional Partners:
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 0.984
epd
Erythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.
    
 0.943
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.852
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
 
   
 0.610
OEG72812.1
Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.594
OEG74097.1
Bifunctional aspartate kinase/homoserine dehydrogenase II; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.594
OEG74978.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.583
OEG73321.1
Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.575
udk
Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.568
OEG72041.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.562
Your Current Organism:
Shewanella colwelliana
NCBI taxonomy Id: 23
Other names: ATCC 39565, ATCC BAA-642 [[Shewanella affinis Ivanova et al. 2004]], Alteromonas colwelliana, CIP 107703 [[Shewanella affinis Ivanova et al. 2004]], KMM 3587 [[Shewanella affinis Ivanova et al. 2004]], S. colwelliana, Shewanella affinis, Shewanella affinis Ivanova et al. 2004, strain LST-W
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.