STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OEG72180.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.957
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.957
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.956
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.943
OEG72386.1
DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.939
OEG73662.1
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.930
OEG75640.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.930
OEG75645.1
Type III restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.930
sbcD
Exonuclease sbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 0.802
OEG72905.1
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.801
Your Current Organism:
Shewanella colwelliana
NCBI taxonomy Id: 23
Other names: ATCC 39565, ATCC BAA-642 [[Shewanella affinis Ivanova et al. 2004]], Alteromonas colwelliana, CIP 107703 [[Shewanella affinis Ivanova et al. 2004]], KMM 3587 [[Shewanella affinis Ivanova et al. 2004]], S. colwelliana, Shewanella affinis, Shewanella affinis Ivanova et al. 2004, strain LST-W
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.