node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OEG73018.1 | OEG73400.1 | BEL05_06360 | BEL05_14140 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
OEG73018.1 | dut | BEL05_06360 | BEL05_15660 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.945 |
OEG73018.1 | tdk | BEL05_06360 | BEL05_07410 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.932 |
OEG73018.1 | thyA | BEL05_06360 | BEL05_10925 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.949 |
OEG73018.1 | tmk | BEL05_06360 | BEL05_14690 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.934 |
OEG73365.1 | OEG73400.1 | BEL05_13955 | BEL05_14140 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.908 |
OEG73365.1 | cdd | BEL05_13955 | BEL05_14535 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.989 |
OEG73365.1 | deoA | BEL05_13955 | BEL05_18165 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.989 |
OEG73365.1 | deoD | BEL05_13955 | BEL05_00980 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
OEG73365.1 | deoD-2 | BEL05_13955 | BEL05_18175 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
OEG73365.1 | tdk | BEL05_13955 | BEL05_07410 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
OEG73400.1 | OEG73018.1 | BEL05_14140 | BEL05_06360 | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
OEG73400.1 | OEG73365.1 | BEL05_14140 | BEL05_13955 | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.908 |
OEG73400.1 | cdd | BEL05_14140 | BEL05_14535 | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.918 |
OEG73400.1 | deoA | BEL05_14140 | BEL05_18165 | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.907 |
OEG73400.1 | deoD | BEL05_14140 | BEL05_00980 | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.951 |
OEG73400.1 | deoD-2 | BEL05_14140 | BEL05_18175 | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.951 |
OEG73400.1 | dut | BEL05_14140 | BEL05_15660 | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.907 |
OEG73400.1 | tdk | BEL05_14140 | BEL05_07410 | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
OEG73400.1 | thyA | BEL05_14140 | BEL05_10925 | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.909 |