Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OEG75292.1Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (483 aa)    
Predicted Functional Partners:
OEG74921.1
Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
  
 0.802
OEG73224.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.793
OEG75258.1
Two-component sensor histidine kinase BarA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.540
OEG73579.1
TMAO reductase system sensor histidine kinase/response regulator TorS; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.533
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.527
OEG75293.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.504
OEG75294.1
RNA polymerase subunit sigma; Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.504
OEG73627.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
 
  
 0.485
OEG75614.1
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
    0.421
Your Current Organism:
Shewanella colwelliana
NCBI taxonomy Id: 23
Other names: ATCC 39565, ATCC BAA-642 [[Shewanella affinis Ivanova et al. 2004]], Alteromonas colwelliana, CIP 107703 [[Shewanella affinis Ivanova et al. 2004]], KMM 3587 [[Shewanella affinis Ivanova et al. 2004]], S. colwelliana, Shewanella affinis, Shewanella affinis Ivanova et al. 2004, strain LST-W
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