Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OEG75919.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (396 aa)    
Predicted Functional Partners:
OEG75920.1
2-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
OEG75048.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
OEG72653.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.997
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.993
OEG72432.1
2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.974
OEG74175.1
Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.959
OEG75050.1
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.945
OEG72431.1
3-methyl-2-oxobutanoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.941
OEG75464.1
Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.918
Your Current Organism:
Shewanella colwelliana
NCBI taxonomy Id: 23
Other names: ATCC 39565, ATCC BAA-642 [[Shewanella affinis Ivanova et al. 2004]], Alteromonas colwelliana, CIP 107703 [[Shewanella affinis Ivanova et al. 2004]], KMM 3587 [[Shewanella affinis Ivanova et al. 2004]], S. colwelliana, Shewanella affinis, Shewanella affinis Ivanova et al. 2004, strain LST-W
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