STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sm9_13764Fe-4S iron sulfur cluster binding protein NifH/FrxC family; Belongs to the NifH/BchL/ChlL family. (264 aa)    
Predicted Functional Partners:
sm9_0152
Methanogenesis marker protein 13; Belongs to the NifD/NifK/NifE/NifN family.
 
 0.996
sm9_1831
Cell wall biosynthesis protein Mur ligase family.
    
 0.948
sm9_1377
Peptidase U32 family.
       0.926
purF
Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
       0.911
nifB
Nitrogenase cofactor biosynthesis protein NifB.
 
  
 0.904
modB
Molybdate ABC transporter permease protein ModB.
  
  
 0.881
mrtA
Methyl-coenzyme M reductase II alpha subunit MrtA; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
      
 0.819
sm9_1892
Prenyltransferase UbiA family; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
  
 0.796
sm9_1381
Geranylgeranyl reductase family protein; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
 
  
 0.794
sm9_1375
Hydrolase HAD superfamily.
     
 0.782
Your Current Organism:
Methanobrevibacter millerae
NCBI taxonomy Id: 230361
Other names: DSM 16643, M. millerae, Methanobrevibacter millerae Rea et al. 2007, Methanobrevibacter sp. ZA-10, OCM 820, strain ZA-10
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