STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sm9_1422Hypothetical protein. (138 aa)    
Predicted Functional Partners:
sm9_1423
TPR repeat-containing protein.
       0.737
comB
2-phosphosulfolactate phosphatase ComB.
   
    0.671
tfe
Transcription initiation factor TFIIE alpha subunit Tfe; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabili [...]
  
   
 0.670
sm9_1424
Hypothetical protein.
 
     0.632
cofE1
F420-0:gamma-glutamyl ligase CofE1.
  
    0.602
sm9_0373
Translation elongation factor aEF-1 beta.
 
     0.579
ribK
Riboflavin kinase RibK; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.549
nusA
Transcription elongation factor NusA-like protein; Participates in transcription termination. Belongs to the NusA family.
  
     0.547
coaA
Pantothenate kinase CoaA.
  
     0.534
adk
Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.
  
     0.497
Your Current Organism:
Methanobrevibacter millerae
NCBI taxonomy Id: 230361
Other names: DSM 16643, M. millerae, Methanobrevibacter millerae Rea et al. 2007, Methanobrevibacter sp. ZA-10, OCM 820, strain ZA-10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.