adk protein (Methanobrevibacter millerae) - STRING interaction network

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adk

Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family. (185 aa)

Predicted Functional Partners:

sm9_1662

0.961

secY

0.941

purB

0.919

thiL

0.911

surE1

0.900

ndk

0.900

surE2

0.900

sm9_2152

0.900

apt

0.900

rpl15

0.864

Your Current Organism:

Methanobrevibacter millerae

NCBI taxonomy Id: 230361
Other names: DSM 16643, M. millerae, Methanobrevibacter millerae Rea et al. 2007, Methanobrevibacter sp. ZA-10, OCM 820, strain ZA-10

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
adk	apt	sm9_1663	sm9_2227	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.	0.900
adk	ndk	sm9_1663	sm9_0844	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.900
adk	purB	sm9_1663	sm9_0165	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.919
adk	rpl15	sm9_1663	sm9_1665	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.864
adk	secY	sm9_1663	sm9_1664	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.941
adk	sm9_1662	sm9_1663	sm9_1662	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	Hypothetical protein.	0.961
adk	sm9_2152	sm9_1663	sm9_2152	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	Hypothetical protein.	0.900
adk	surE1	sm9_1663	sm9_0067	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	5'-nucleotidase SurE1; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.900
adk	surE2	sm9_1663	sm9_1095	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	5'-nucleotidase SurE2; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.900
adk	thiL	sm9_1663	sm9_2304	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	Thiamine-monophosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.	0.911
apt	adk	sm9_2227	sm9_1663	Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	0.900
apt	ndk	sm9_2227	sm9_0844	Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.	Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.508
apt	purB	sm9_2227	sm9_0165	Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.	Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.986
apt	sm9_2152	sm9_2227	sm9_2152	Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.	Hypothetical protein.	0.911
apt	surE1	sm9_2227	sm9_0067	Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.	5'-nucleotidase SurE1; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.923
apt	surE2	sm9_2227	sm9_1095	Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.	5'-nucleotidase SurE2; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.923
ndk	adk	sm9_0844	sm9_1663	Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family.	0.900
ndk	apt	sm9_0844	sm9_2227	Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.	0.508
ndk	purB	sm9_0844	sm9_0165	Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.428
ndk	rpl15	sm9_0844	sm9_1665	Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.882