node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
eif1a | psmA | sm9_1906 | sm9_0809 | Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.728 |
eif1a | psmB | sm9_1906 | sm9_2049 | Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.558 |
eif1a | rpl40e | sm9_1906 | sm9_0932 | Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Ribosomal protein L40e Rpl40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.588 |
eif1a | sm9_0551 | sm9_1906 | sm9_0551 | Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Hypothetical protein. | 0.878 |
nifS | psmB | sm9_0798 | sm9_2049 | Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.704 |
pan | psmA | sm9_0675 | sm9_0809 | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.932 |
pan | psmB | sm9_0675 | sm9_2049 | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.919 |
pan | rpl40e | sm9_0675 | sm9_0932 | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | Ribosomal protein L40e Rpl40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.897 |
pan | sm9_0330 | sm9_0675 | sm9_0330 | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | ATPase. | 0.569 |
pan | sm9_0551 | sm9_0675 | sm9_0551 | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | Hypothetical protein. | 0.964 |
pan | sm9_1303 | sm9_0675 | sm9_1303 | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | ATPase AAA family. | 0.536 |
pan | sm9_2192 | sm9_0675 | sm9_2192 | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | Proteasome-activating nucleotidase. | 0.902 |
psmA | eif1a | sm9_0809 | sm9_1906 | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.728 |
psmA | pan | sm9_0809 | sm9_0675 | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.932 |
psmA | psmB | sm9_0809 | sm9_2049 | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.986 |
psmA | rpl40e | sm9_0809 | sm9_0932 | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | Ribosomal protein L40e Rpl40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.883 |
psmA | sm9_0330 | sm9_0809 | sm9_0330 | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | ATPase. | 0.833 |
psmA | sm9_0551 | sm9_0809 | sm9_0551 | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | Hypothetical protein. | 0.947 |
psmA | sm9_1303 | sm9_0809 | sm9_1303 | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | ATPase AAA family. | 0.846 |
psmA | sm9_2192 | sm9_0809 | sm9_2192 | Proteasome alpha subunit PsmA; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | Proteasome-activating nucleotidase. | 0.931 |