STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3KCX6AP endonuclease. (467 aa)    
Predicted Functional Partners:
A0A5C3KTW3
DNase I-like protein.
    
 0.990
A0A5C3LB58
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
    
 0.989
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.
  
 
 0.889
A0A5C3KUM4
ERCC4 domain-containing protein.
   
 
 0.859
A0A5C3KZE6
DNA repair protein rad10.
   
 
 0.822
A0A5C3KIZ7
XPA_C domain-containing protein.
   
 
 0.797
A0A5C3LBK7
DNA polymerase.
    
 
 0.783
UNG1
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 
 0.781
A0A5C3KLV2
DNA glycosylase.
   
 
 0.743
A0A5C3KYU4
Uncharacterized protein.
   
 
 0.743
Your Current Organism:
Coprinopsis marcescibilis
NCBI taxonomy Id: 230819
Other names: C. marcescibilis, Coprinopsis marcescibilis (Britzelm.) Oerstadius & E. Larss. 2008, Psathyrella marcescibilis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.