Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Map3k12Mitogen-activated protein kinase kinase kinase 12. (893 aa)    
Predicted Functional Partners:
Mycbp2
MYC binding protein 2.
    
 0.983
ENSPEMP00000024711
annotation not available
    
 0.973
Map3k13
Mitogen-activated protein kinase kinase kinase 13.
     
  0.932
Casp9
Caspase 9.
     
 0.832
Fra10ac1
FRA10AC1 homolog (human).
    
 
 0.796
Mapk8ip1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 
 0.726
Mbip
MAP3K12 binding inhibitory protein 1.
    
 
 0.648
Map2k4
Mitogen-activated protein kinase kinase 4.
    
 
 0.587
Mapk8ip2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 
 0.586
Tars
threonyl-tRNA synthetase 1.
      
 0.586
Your Current Organism:
Peromyscus maniculatus
NCBI taxonomy Id: 230844
Other names: P. maniculatus bairdii, Peromyscus maniculatus bairdii, prairie deer mouse
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