STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smpdl3aSphingomyelin phosphodiesterase, acid-like 3A. (445 aa)    
Predicted Functional Partners:
Npc2
NPC intracellular cholesterol transporter 2.
   
 
  0.706
Gstt4
Glutathione S-transferase theta-4.
      
 0.572
Brinp1
BMP/retinoic acid inducible neural specific 1.
      
 0.572
Btbd10
BTB domain containing 10.
      
 0.572
Ttc9c
Tetratricopeptide repeat domain 9C.
      
 0.568
Sqor
Sulfide quinone oxidoreductase.
      
 0.564
Cdc40
Cell division cycle 40.
      
 0.508
Vwde
Von Willebrand factor D and EGF domains.
      
 0.473
ENSPEMP00000030688
annotation not available
      
 0.473
Kctd20
Potassium channel tetramerization domain containing 20.
      
 0.459
Your Current Organism:
Peromyscus maniculatus
NCBI taxonomy Id: 230844
Other names: P. maniculatus bairdii, Peromyscus maniculatus bairdii, prairie deer mouse
Server load: low (20%) [HD]