STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NsmafNeutral sphingomyelinase (N-SMase) activation associated factor. (920 aa)    
Predicted Functional Partners:
Tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.962
Smpd2
Sphingomyelin phosphodiesterase 2, neutral.
     
 0.924
Atg5
Autophagy related 5.
    
 0.899
Atg12
Autophagy related 12.
    
 0.876
Tnfrsf25
Tumor necrosis factor receptor superfamily, member 25.
    
 0.832
Plekhg5
Pleckstrin homology and RhoGEF domain containing G5.
    
 0.832
Plekhg6
Pleckstrin homology and RhoGEF domain containing G6.
    
 0.832
Atg16l1
Autophagy related 16 like 1.
    
0.797
Atg16l2
Autophagy related 16 like 2.
    
0.797
Rack1
Receptor for activated C kinase 1.
    
0.759
Your Current Organism:
Peromyscus maniculatus
NCBI taxonomy Id: 230844
Other names: P. maniculatus bairdii, Peromyscus maniculatus bairdii, prairie deer mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.