STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (231 aa)    
Predicted Functional Partners:
fbp
Fructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.999
gap
Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glycerol phosphate from D-glyceraldehyde 3-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
CF15_05410
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
CF15_06975
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
CF15_03600
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
pgk
Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family.
 
 0.995
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.992
CF15_02710
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.988
CF15_06735
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.973
CF15_06730
Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.972
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
Server load: medium (74%) [HD]