STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIHypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (388 aa)    
Predicted Functional Partners:
rpl11
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
 
 0.999
CF15_00835
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.997
CF15_01750
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.992
CF15_00980
Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.986
CF15_01410
tRNA-Lys; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.978
CF15_01795
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.978
CF15_01800
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.978
CF15_02065
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.978
CF15_03365
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.841
CF15_04700
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.819
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.