STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CF15_01460Phosphomethylpyrimidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)    
Predicted Functional Partners:
CF15_07570
Phosphomethylpyrimidine kinase; Catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
CF15_04920
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.970
thi4
Ribulose-1,5-biphosphate synthetase; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
  
  
 0.937
CF15_00980
Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.896
CF15_00835
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.834
CF15_08060
Dehypoxanthine futalosine cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.703
CF15_08065
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.703
thiI
Hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.661
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family.
    
 0.605
CF15_01455
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.594
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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