STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxSPyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (352 aa)    
Predicted Functional Partners:
pdxT
Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
 0.999
CF15_01540
Ribose-phosphate pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 
  0.996
CF15_05610
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.996
CF15_06730
Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.970
CF15_06735
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.970
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.668
CF15_07570
Phosphomethylpyrimidine kinase; Catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.610
CF15_07905
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
  
 0.599
CF15_05525
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.516
gatA
Hypothetical protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
   
 
 0.511
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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