psmB-2 protein (Pyrodictium occultum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

psmB-2

Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (204 aa)

Predicted Functional Partners:

psmB

0.999

pan

0.896

psmA

0.852

nfi

0.825

CF15_00915

0.734

CF15_05025

0.654

CF15_01365

0.590

CF15_05205

0.590

thsA

0.547

CF15_00400

0.537

Your Current Organism:

Pyrodictium occultum

NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CF15_00400	psmA	CF15_00400	CF15_00850	Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family.	Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.698
CF15_00400	psmB	CF15_00400	CF15_02190	Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.474
CF15_00400	psmB-2	CF15_00400	CF15_02205	Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.537
CF15_00400	thsA	CF15_00400	CF15_03805	Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family.	Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family.	0.680
CF15_00915	CF15_01365	CF15_00915	CF15_01365	50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.774
CF15_00915	CF15_05025	CF15_00915	CF15_05025	50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.774
CF15_00915	CF15_05205	CF15_00915	CF15_05205	50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.774
CF15_00915	pan	CF15_00915	CF15_05070	50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.	Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]	0.899
CF15_00915	psmA	CF15_00915	CF15_00850	50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.	Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.734
CF15_00915	psmB	CF15_00915	CF15_02190	50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.734
CF15_00915	psmB-2	CF15_00915	CF15_02205	50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.734
CF15_01365	CF15_00915	CF15_01365	CF15_00915	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.	0.774
CF15_01365	pan	CF15_01365	CF15_05070	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]	0.475
CF15_01365	psmA	CF15_01365	CF15_00850	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.603
CF15_01365	psmB	CF15_01365	CF15_02190	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.590
CF15_01365	psmB-2	CF15_01365	CF15_02205	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.590
CF15_05025	CF15_00915	CF15_05025	CF15_00915	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.	0.774
CF15_05025	pan	CF15_05025	CF15_05070	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]	0.516
CF15_05025	psmA	CF15_05025	CF15_00850	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.590
CF15_05025	psmB	CF15_05025	CF15_02190	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.590