Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CF15_03050Cren protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)    
Predicted Functional Partners:
CF15_01790
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.637
CF15_03215
DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.631
rpl6
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.623
rpl32e
50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL32 family.
   
   0.623
rpl19e
50S ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
   
   0.623
rpl18
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
   0.623
rps5
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
   
   0.622
rpl30
50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.622
rpl15
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.605
rps3ae
30S ribosomal protein S3Ae; The function for this protein is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS1 family.
    
   0.590
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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