Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppaInorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (179 aa)    
Predicted Functional Partners:
atpD
ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
  0.980
atpB
ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
   
 
 0.976
atpA
ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
   
 
 0.975
CF15_05235
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family.
   
 
 0.968
CF15_05240
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.968
CF15_05245
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.968
CF15_05225
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.946
CF15_05270
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.939
eif5a
Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
   
  
 0.853
rpl13
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.835
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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