Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF15_04535Diadenosine tetraphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)    
Predicted Functional Partners:
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.
  
 
  0.719
CF15_03895
GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
     0.718
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
 
    0.701
tbp
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
   
  0.661
CF15_05770
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
  
   0.605
CF15_04225
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.578
CF15_04530
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.572
CF15_08025
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.511
CF15_01790
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.488
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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