Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CF15_04585Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)    
Predicted Functional Partners:
cobD
Hypothetical protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
  0.993
cobS
Hypothetical protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.962
CF15_04580
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0284 family.
 
     0.937
CF15_04590
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.928
CF15_04595
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.919
CF15_04610
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.780
CF15_04615
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.701
CF15_03360
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.671
srp19
Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
 
     0.668
CF15_04755
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.652
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.