Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
CF15_04700Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)    
Predicted Functional Partners:
CF15_03765
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.927
CF15_01505
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.910
CF15_01975
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.881
CF15_06760
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.732
thiI
Hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.722
CF15_00835
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.700
CF15_03040
Cytidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.675
CF15_00570
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.651
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
    0.648
CF15_04705
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.620
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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