Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF15_04790Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)    
Predicted Functional Partners:
CF15_07450
acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.941
CF15_08155
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.941
CF15_01880
Acetyl-coenzyme A synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.801
CF15_04785
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.642
thiI
Hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.636
gatA
Hypothetical protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
    
  0.629
CF15_01280
Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.607
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
    
  0.575
CF15_01600
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.526
CF15_02045
Hydrogenase maturation protein HypF; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.462
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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