| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CF15_00915 | CF15_05065 | CF15_00915 | CF15_05065 | 50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. | XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.716 |
| CF15_00915 | pan | CF15_00915 | CF15_05070 | 50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.899 |
| CF15_00915 | psmA | CF15_00915 | CF15_00850 | 50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.734 |
| CF15_00915 | psmB | CF15_00915 | CF15_02190 | 50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.734 |
| CF15_00915 | psmB-2 | CF15_00915 | CF15_02205 | 50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.734 |
| CF15_00915 | tuf | CF15_00915 | CF15_02120 | 50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.761 |
| CF15_05055 | CF15_05065 | CF15_05055 | CF15_05065 | tRNA 2'-O-methylase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.794 |
| CF15_05055 | hflX | CF15_05055 | CF15_05060 | tRNA 2'-O-methylase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Hypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.897 |
| CF15_05055 | pan | CF15_05055 | CF15_05070 | tRNA 2'-O-methylase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.653 |
| CF15_05065 | CF15_00915 | CF15_05065 | CF15_00915 | XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.716 |
| CF15_05065 | CF15_05055 | CF15_05065 | CF15_05055 | XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA 2'-O-methylase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.794 |
| CF15_05065 | hflX | CF15_05065 | CF15_05060 | XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.786 |
| CF15_05065 | pan | CF15_05065 | CF15_05070 | XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.828 |
| CF15_08100 | guaA | CF15_08100 | CF15_00065 | Membrane protease subunit, stomatin/prohibitin-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.446 |
| CF15_08100 | hflX | CF15_08100 | CF15_05060 | Membrane protease subunit, stomatin/prohibitin-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.698 |
| CF15_08100 | pan | CF15_08100 | CF15_05070 | Membrane protease subunit, stomatin/prohibitin-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.663 |
| guaA | CF15_08100 | CF15_00065 | CF15_08100 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Membrane protease subunit, stomatin/prohibitin-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.446 |
| guaA | hflX | CF15_00065 | CF15_05060 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.498 |
| guaA | pan | CF15_00065 | CF15_05070 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.569 |
| hflX | CF15_05055 | CF15_05060 | CF15_05055 | Hypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | tRNA 2'-O-methylase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.897 |