STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CF15_05095Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.962
CF15_05100
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.699
CF15_05105
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
0.584
taw3
Hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family.
       0.574
CF15_06760
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.492
thiI
Hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
    
 
 0.467
CF15_05110
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
0.467
CF15_03425
GTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.404
CF15_05115
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
0.401
CF15_05085
Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.400
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.