STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CF15_055656-O-methylguanine DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)    
Predicted Functional Partners:
CF15_00945
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.663
CF15_01010
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.537
CF15_03705
Universal stress protein UspA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.537
CF15_07865
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.537
CF15_03060
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.454
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
   
 
 0.418
CF15_07840
Endonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.416
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.