STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (431 aa)    
Predicted Functional Partners:
CF15_06765
Tryptophan synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.999
CF15_06795
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.995
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.987
CF15_06785
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.857
CF15_06790
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.838
trpF
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family.
    
 0.833
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
    
 0.782
CF15_06760
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.626
CF15_06755
alanyl-tRNA editing protein AlaX; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.402
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.