Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
pepAPeptidase M17; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (489 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.960
CF15_03365
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.956
CF15_06855
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.934
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.679
CF15_03425
GTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.518
CF15_07610
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.497
CF15_06760
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.482
CF15_04265
Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.481
CF15_07505
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.481
CF15_00250
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family.
  
 
 0.479
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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